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Hiroshi Asanuma Selected Research

Charybdotoxin (ChTX)

12/2004Opening of Ca2+-activated K+ channels is involved in ischemic preconditioning in canine hearts.
6/2003Eicosapentaenoic acid reduces myocardial injury induced by ischemia and reperfusion in rabbit hearts.
9/2002Amelioration of ischemia- and reperfusion-induced myocardial injury by the selective estrogen receptor modulator, raloxifene, in the canine heart.

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Hiroshi Asanuma Research Topics

Disease

32Heart Failure
01/2019 - 10/2003
22Infarction (Infarctions)
10/2018 - 01/2002
17Reperfusion Injury
12/2017 - 01/2002
16Neoplasms (Cancer)
09/2021 - 03/2002
16Myocardial Infarction
10/2018 - 01/2002
15Ischemia
10/2020 - 01/2002
11Myocardial Ischemia (Ischemic Heart Diseases)
05/2015 - 07/2002
10Fibrosis (Cirrhosis)
01/2019 - 10/2006
9Hypertrophy
01/2019 - 09/2002
9Cardiomegaly (Heart Hypertrophy)
01/2016 - 01/2002
6Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 01/2018
6Diabetes Mellitus
01/2019 - 10/2006
6Glucose Intolerance
08/2017 - 02/2006
6Coronary Occlusion
12/2004 - 01/2002
5Prostatic Neoplasms (Prostate Cancer)
04/2021 - 10/2015
5Body Weight (Weight, Body)
10/2008 - 09/2002
4Hypotension (Low Blood Pressure)
11/2021 - 10/2007
4Ureteral Obstruction
10/2011 - 09/2009
4Ventricular Fibrillation
06/2006 - 01/2002
3Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2022 - 10/2006
3Bradycardia
01/2019 - 02/2009
3Urinary Bladder Neoplasms (Bladder Cancer)
10/2015 - 02/2003
3Cardiovascular Diseases (Cardiovascular Disease)
01/2015 - 05/2010
2Hemorrhage
07/2022 - 10/2015
2Left Ventricular Dysfunction
09/2020 - 07/2006
2Vesico-Ureteral Reflux (Vesicoureteral Reflux)
11/2018 - 07/2010
2Stroke (Strokes)
10/2018 - 08/2017
2Unstable Angina
10/2018 - 08/2017
2Neoplasm Metastasis (Metastasis)
01/2018 - 01/2015
2Inflammation (Inflammations)
01/2016 - 09/2009
2Hyperplasia
10/2015 - 04/2005
2Hypoxia (Hypoxemia)
02/2015 - 01/2014
2Chronic Renal Insufficiency
11/2014 - 07/2010
2Cardiac Arrhythmias (Arrythmia)
04/2013 - 06/2006
2Insulin Resistance
08/2012 - 05/2009

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
01/2022 - 09/2002
12Adenosine (Adenocard)FDA LinkGeneric
09/2019 - 01/2002
8Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2017 - 01/2002
7Adenosine Triphosphate (ATP)IBA
02/2015 - 09/2002
6Glucose (Dextrose)FDA LinkGeneric
09/2020 - 02/2006
65'-Nucleotidase (5' Nucleotidase)IBA
06/2008 - 09/2003
6Phosphotransferases (Kinase)IBA
06/2006 - 09/2002
5Brain Natriuretic Peptide (Natrecor)FDA Link
02/2017 - 01/2012
5Purinergic P1 Receptors (Adenosine Receptor)IBA
05/2015 - 01/2002
5NG-Nitroarginine Methyl Ester (L-NAME)IBA
06/2003 - 01/2002
4CollagenIBA
01/2019 - 09/2009
4Dipeptidyl-Peptidase IV InhibitorsIBA
01/2019 - 05/2013
4CytokinesIBA
01/2016 - 06/2011
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2016 - 09/2009
4Raloxifene Hydrochloride (Evista)FDA Link
06/2004 - 01/2002
4Selective Estrogen Receptor Modulators (SERM)IBA
06/2004 - 01/2002
3C-Reactive ProteinIBA
08/2021 - 01/2018
3PotassiumIBA
01/2020 - 09/2002
3Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2019 - 09/2002
3AdiponectinIBA
10/2018 - 12/2009
3Hormones (Hormone)IBA
02/2017 - 05/2013
3Pharmaceutical PreparationsIBA
01/2016 - 04/2005
3Glucagon-Like Peptide 1 (GLP 1)IBA
05/2015 - 05/2013
3Anti-Arrhythmia AgentsIBA
04/2013 - 01/2005
3Angiotensin IIIBA
01/2012 - 10/2003
3Interleukin-18 (Interleukin 18)IBA
10/2011 - 09/2009
3salicylhydroxamic acid (SHAM)IBA
10/2011 - 06/2011
3Cadherins (E-Cadherin)IBA
06/2011 - 09/2009
3Histamine (Histamine Dihydrochloride)FDA Link
11/2010 - 05/2006
3WortmanninIBA
06/2006 - 10/2004
3KATP ChannelsIBA
12/2005 - 01/2003
3Protein Kinase CIBA
12/2005 - 07/2004
3Charybdotoxin (ChTX)IBA
12/2004 - 09/2002
38-(4-sulfophenyl)theophyllineIBA
10/2004 - 01/2002
3Nitric Oxide Synthase (NO Synthase)IBA
08/2004 - 01/2002
370-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
04/2003 - 09/2002
2HDL CholesterolIBA
09/2020 - 08/2012
2AldosteroneIBA
01/2020 - 07/2005
2Uric Acid (Urate)IBA
06/2019 - 08/2012
2Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2019 - 03/2013
2VildagliptinIBA
01/2019 - 05/2013
2Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA
01/2019 - 05/2013
2MethylprednisoloneFDA LinkGeneric
01/2019 - 03/2013
2Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
11/2018 - 01/2002
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2018 - 05/2010
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2018 - 03/2002
2HydrogenIBA
06/2017 - 06/2012
2Fibroblast Growth Factor-23IBA
02/2017 - 11/2014
2Messenger RNA (mRNA)IBA
01/2016 - 07/2010
2Liposomes (Liposome)IBA
01/2016 - 02/2009
2AMP-Activated Protein KinasesIBA
01/2015 - 05/2009
2IncretinsIBA
01/2015 - 05/2013
2human NPPA protein (carperitide)IBA
08/2014 - 12/2009

Therapy/Procedure

21Therapeutics
07/2022 - 01/2002
6Percutaneous Coronary Intervention
12/2022 - 02/2004
5Nephrectomy
10/2020 - 03/2006
4Prostatectomy (Retropubic Prostatectomy)
11/2022 - 01/2019
4Intravenous Administration
04/2013 - 01/2005
3Adrenalectomy
11/2021 - 04/2012
3Castration
04/2021 - 07/2020
2Catheters
07/2022 - 03/2007
2Kidney Transplantation
03/2020 - 03/2013
2Secondary Prevention
10/2018 - 05/2010
2Drug Therapy (Chemotherapy)
01/2018 - 08/2016
2Ligation
01/2012 - 04/2005